Southern Research concludes free genetic testing program in Alabama

Residents of Alabama can no longer sign up for the free clinical genetic testing program known as Catalyst. Southern Research closed enrollment on Sept. 30, ending a two-year initiative that distributed testing kits to households across all 67 counties in the state.

The program provided eligible residents with mail-order kits that required only a cheek swab for analysis. Since its launch in October 2024, Catalyst processed samples from more than 9,300 participants. Of those, the program returned more than 5,600 clinical genetic results.

The tests examined specific inherited risks for conditions including heart disease, type 2 diabetes, and certain cancers. The results also detailed how participants' genes might affect their response to more than 70 common medications. This data includes potential side effects or reduced effectiveness of specific drugs. Participants used this information to discuss prevention strategies and treatment options with their physicians.

Dr. Oliver Hampton, Catalyst's chief data officer and principal investigator, stated that the program aimed to see what happens when clinical genetic testing is made free and easy for anyone in the state. The initiative was funded by grants from the state of Alabama and the city of Birmingham. To reach a wide audience, Southern Research staff attended more than 400 community events in addition to mailing kits directly to homes.

The program also generated data for research on health needs across Alabama. Dr. Hampton noted that participants gained a clearer picture of their own health, including inherited risks and optimal medication choices. He said the collective data provides a clearer view of the state's health and areas requiring focused attention.

Existing participants can continue to receive program services. This includes processing of eligible samples, access to results through the participant portal, and genetic counseling. Enrolled participants who have not yet returned their samples have 90 days from the date they ordered their tests to mail them in. Southern Research says enrollment may reopen if additional funding becomes available.

The genetic counseling component helped participants understand their results and how to share them with family members and doctors. An increased genetic risk indicated by the tests does not guarantee a person will develop a condition, but it provides specific data for health planning. The program's current grant period has ended, but support for those already enrolled remains active.